Computational Approaches in Metabolic Engineering
نویسندگان
چکیده
منابع مشابه
Computational Approaches in Metabolic Engineering
Metabolic engineering involves the adjustment of metabolic and regulatory processes to improve desired cellular behaviors, such as the production of proteins and chemicals. Since cellular metabolic and regulatory networks are often large and complex, the construction and analysis of computational models of these networks can be useful for identifying current network states and evaluating the ef...
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A great variety of software applications are now employed in the metabolic engineering field. These applications have been created to support a wide range of experimental and analysis techniques. Computational tools are utilized throughout the metabolic engineering workflow to extract and interpret relevant information from large data sets, to present complex models in a more manageable form, a...
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Traditional metabolic engineering analyzes biosynthetic and physiological pathways, identifies bottlenecks, and makes targeted genetic modifications with the ultimate goal of increasing the production of high-value products in living cells. Such efforts have led to the development of a variety of organisms with industrially relevant properties. However, there are a number of cellular phenotypes...
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Metabolic engineering modifies cellular function to address various biochemical applications. Underlying metabolic engineering efforts are a host of tools and knowledge that are integrated to enable successful outcomes. Concurrent development of computational and experimental tools has enabled different approaches to metabolic engineering. One approach is to leverage knowledge and computational...
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1Department of Environmental Robotics, Faculty of Engineering, University of Miyazaki, 1-1 Gakuen Kibanadai-nishi, Miyazaki-shi 889-2192, Japan 2Department of Intellectual Information Engineering, Faculty of Engineering, University of Toyama, No. 5506, Information Technology Building (G9), Gofuku 3190, Toyama 930-8555, Japan 3Research Institute of Robotics, Shanghai Jiao Tong University, No. 80...
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ژورنال
عنوان ژورنال: Journal of Biomedicine and Biotechnology
سال: 2010
ISSN: 1110-7243,1110-7251
DOI: 10.1155/2010/207414